objective(s): buthionine sulfoximine (bso) inhibits synthesis of glutathione as the main intracellular antioxidant. the aim of the present study is to investigate the effect of bso-induced oxidative stress on histological structure of testis, testosterone secretion and semen parameters. materials and methods: thirty male balb/c mice were divided into 3 groups. in control group, the mice did not...

o bjective : increased levels of oxidative stress markers in periodontitis have been reported by recent studies. malondialdehyde (mda) and superoxide dismutase (sod) are both in- creased during oxidative stress. the aim of this study was to detect and measure the level of oxidative stress markers in peri-implant crevicular fluid (picf). their correlation with peri-implant clinical parameters wa...

abstract         background and objective: methamphetamine has strong stimulating effects on various systems of the human body. the aim of this study was to evaluate the hematological and biochemical parameters in methamphetamine addicts and to compare them with healthyindividuals.      methods: this is a retrospective case-control study that was conducted in 1390-91 in ibn sina hospital in shi...

Background: Although studies are available on lipid peroxidation products and the antioxidant status in experimental animals, a detailed report on human exposed to diesel combustion nanoparticles is meagre. We aimed to study the variation in oxidative stress markers among exposures. Method:A cross-sectional study during the period between 2015-2017 was conducted among 500 male garage workers of...

Background: Recent studies have suggested the importance of oxidant/antioxidant status in initiation and progression of breast cancer. The aim of this study was to evaluate oxidative stress markers in breast cancer patients before and after 3 cycles of chemotherapy with adriamycin and cytoxan (AC). Also, in this study the effect of age and the stage of disease on oxidative stress markers were c...

objective(s):hyperglycemia mediated oxidative stress plays a key role in the pathogenesis of diabetic complications like nephropathy. in the present study, we evaluated the effect of ethanolic extract of ensete superbum seeds (esse) on renal dysfunction and oxidative stress in streptozotocin-induced diabetic rats. materials and methods:glucose, hba1c, total protein, albumin, renal function mark...

Oxidative stress represents a situation where there is an imbalance between the reactive oxygen species (ROS) and the availability and the activity of antioxidants. This balance is disturbed by increased generation of free radicals or decreased antioxidant activity. It is very important to develop methods and find appropriate biomarkers that may be used to assess oxidative stress in vivo. It is...